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RESEARCH PUBLICATIONS

(ASD-CARC Researchers, ASPIRE Training Program Trainees, Other Trainees)


2012

Feldman M, RA Ward, D Savona, K Regehr, K Parker, M Hudson, H Penning, JJ Holden (2012) Development and initial validation of a parent report measure of the behavioral development of infants at risk for autism spectrum disorders. Journal of Autism and Developmental Disorders 42: 13-22.


2011

Coo H, H Ouellette-Kuntz, M Lam, CT Yu, D Dewey D, FP Bernier, AE Chudley, PE Hennessey, MM Breitenbach, AL Noonan, JJA Holden, MES Lewis (in press). Factors associated with the age at which children are diagnosed with an autism spectrum disorder in six regions of Canada. Chronic Diseases in Canada.

Harvard C, E Strong, E Mercier, R Colnaghi, D Alcantara, E Chow, S Martell, C Tyson, M Hrynchak, B McGillivray, S Hamilton, S Marles, A Mhanni, AJ Dawson, P Pavlidis, Y Qiao, JJ Holden, SM Lewis, M O'Driscoll, E Rajcan-Separovic (2011) Understanding the impact of 1q21.1 copy number variant. Orphanet J Rare Disorders, 6: 54.

Liu X, P Malenfant, C Reesor, A Lee, ML Hudson, C Harvard, Y Qiao, AM Persico, IL Cohen, AE Chudley, C Forster-Gibson, E Rajcan-Separovic, ME Lewis, JJ Holden (2011) 2p15-p16.1 microdeletion syndrome: molecular characterization and association of the OTX1 and XPO1 genes with autism spectrum disorders. European Journal of Human Genetics, 19: 1264-70.

Liu X, F Solehdin, IL Cohen, MG Gonzalez, EC Jenkins, ME Lewis, JJ Holden (2011) Population- and family-based studies associate the MTHFR gene with idiopathic autism in simplex families. Journal of Autism and Developmental Disorders, 41: 938-44.

MacPherson LF, CGP Sousa, KM Thomson, TL Martin, S Salem, GL Martin & CT Yu (2011). Does the Assessment of Basic Learning Abilities predict four-choice discrimination learning for persons with developmental disabilities? Journal on Developmental Disabilities, 17, 38-46

P Malenfant, X Liu, ML Hudson, Y Qiao, M Hrynchak, N Riendeau, MJ Hildebrand, IL Cohen, AE Chudley, C Forster-Gibson, EC Mickelson, E Rajcan-Separovic, ME Lewis, JJ Holden (2011) Association of GTF2i in the Williams-Beuren Syndrome Critical Region with Autism Spectrum Disorders. Journal of Autism and Developmental Disorders [Nov 3 Epub ahead of print]

Malisza KL, C Clancy, D Shiloff, J Holden, C Jones, K Paulson, CT Yu, R Summers & AE Chudley (2011) Functional magnetic resonance imaging of facial information processing in children with autistic disorder, attention deficit hyperactivity disorder and typically developing controls. International Journal of Adolescent Medicine and Health, 23: 269-77.

Malisza KL, C Clancy, D Shiloff, D Foreman, J Holden, C Jones, K Paulson, R Summers, CT Yu & AE Chudley (2011). Functional evaluation of hidden figures object analysis in children with autistic disorder. Journal of Autism and Developmental Disabilities, 41, 13-22.

Marion C, GL Martin, CT Yu & C Buhler (2011). Teaching Children with Autism  to Mand “What is it?” Research in Autism Spectrum Disorders, 5, 1584-1597.

Ouellette-Kuntz H, H Coo, CT Yu, MES Lewis, D Dewey, PE Hennessey, PD Jackman, MM Breitenbach, JJA Holden (in press). National Epidemiologic Database for the Study of Autism in Canada (NEDSAC). Chronic Diseases in Canada

Roy-Wsiaki G, C Marion, GL Martin & CT Yu (in press). Teaching a child with autism to request information by asking “what?” Developmental Disabilities Bulletin.

Viel J, J Wightman, C Marion, B Jeanson, GL Martin, CT Yu & A Verbeke (2011). Does mastery of ABLA level 6 make it easier for children with autism to learn to name objects? Research in Autism Spectrum Disorders, 5, 1370-1377. doi:10.1016/j.rasd.2011.01.019



2010

Cohen IL, T Rovito Gomez, MG Gonzalez, EM Lennon, BZ Karmel & JM Gardner (2010) Parent PDD Behavior Inventory Profiles of Young Children Classified According to Autism Diagnostic Observation Schedule-Generic and Autism Diagnostic Interview-Revised Criteria. Journal of Autism and Developmental Disorders, 40(2). 246-254.

Cohen IL, JA Tsiouris, MJ Flory, SY Kim, R Freedland, G Heaney, J Pettinger & TW Brown (2010) A large scale study of the psychometric characteristics of the IBR Modified Overt Aggression Scale: Findings and evidence for increased self-destructive behaviors in adult females with autism spectrum disorder. Journal of Autism and Developmental Disorders. 40(5). 599-609.

Cohen IL, X Liu, MES Lewis, A Chudley, C Forster-Gibson, M Gonzalez, E Jenkins, WT Brown, JJA Holden (2010) Autism severity is associated with child and maternal MAOA genotypes. Clin Genet. 2010 May 22.

Fisch GS, N Carpenter, PN Howard-Peebles, JJA Holden, J Tarleton, R Simensen (2010) The course of cognitive-behavioral development in children with the FMR1 mutation, Williams-Beuren syndrome and neurofibromatosis type 1: The effect of gender. Am J Med Gene A 152: 1498-1509. 

Jeansen, B., Thiessen, C., Thomson, K., Vermeulen, R., Martin, G.L., & Yu, C. T (2010). Field testing of the discrete-trials teaching evaluation form. Research in Autism Spectrum Disorders, 4, 718-723.

Lee, M.S.H., Yu, C.T., Martin, T.L., & Martin, G.L. (2010). On the relation between reinforcer efficacy and preference. Journal of Applied Behavior Analysis, 43, 95-100. 

Liu X, F Solehdin, IL Cohen, MG Gonzales, EC Jenkins, MES Lewis, JJA Holden. Population and Family-Based Studies Association the MTHFR Gene in Simplex Families with Idiopathic Autism. J Autism Dev Disord, Nov 12, 2010 [Epub ahead of print] 

Malisza KL, Clancy C, Shiloff D, Foreman D, Holden J, Jones C, Paulson K, Summers R, Yu CT, Chudley AE. (2010). Functional Evaluation of Hidden Figures Object Analysis in Children with Autistic Disorder. Journal of Autism and Developmental Disorders. Epub April 22 2010.

Malisza KL, C Clancy, D Shiloff, JJA Holden, C Jones, K Paulson, CT Yu, R Summers, AE Chudley (2010) Functional Magnetic Resonance Imaging of facial information processing in children with autistic disorder, attention deficit hyperactivity disorder and typically developing controls. J Autism Dev Disord in press.

Malisza, K.L., Martin, T.L., Shiloff, D., & Yu, C.T. (2010). Reactions of young children to the MRI scanner environment. Magnetic Resonance in Medicine, 64, 377-381. 

Martin, T.L., Shooshtari, S., Temple, B., & Yu, C.T. (2010). Facilitating and impeding factors for knowledge translation in developmental disabilities: outcomes of community-based workshops. Journal on Developmental Disabilities, 16(3), 41-47.

McGuinness TM, Lewis S. (in press) Update on Autism and Vaccines. J Psychosoc Nurs Ment Health Serv. 2010 May 26:1-4.

Montgomery, J. M., McCrimmon, A. W., Schwean, V. L., & Saklofske, D. H.  (2010).  Emotional Intelligence in Asperger Syndrome: Implications of Dissonance between Cognition and Affect.  Education and Training in Developmental Disabilities, 45(4), 566-582.

Noor A, A Whibley, CR Marshall, PJ Gianakopoulos, A Piton, AR Carson, M Orlic-Milacic,  A Lionel, D Sato, D Pinto, I Drmic, C Noakes, L Senman, X Zhang, R Mo, J Gauthier, J Crosbie, AT Pagnamenta, J Munson, AM Estes, A Fiebig, A Franke, S Schreiber, AFR Stewartt R Roberts, R McPherson, SJ Guter, EH Cook Jr, G Dawson, GD Schellenberg, A Battaglia, E Maestrini, Autism Genome Project Consortium, L Jeng, T Hutchison, E Rajcan-Separovic, AE Chudley, MES Lewis, X Liu, JJA Holden, B Fernandez, L Zwaigenbaum, SE Bryson, W Roberts, P Szatmari, L Gallagher, MR Stratton, J Gecz, AF Brady, CE Schwartz, RJ Schachar, AP Monaco,  GA Rouleau, C-C Hui, FL Raymond, SW Scherer, JB Vincent (2010) Disruption at the PTCHD1 locus on Xp22.11 in autism spectrum disorder and intellectual disability. Science Translational Medicine, 2010 Sep 15;2(49):49ra68. 

Ouellette-Kuntz H, S Shooshtari, B Temple, M Brownell, C Burchill, CT Yu, JJA Holden, B Hennen (2010) Estimating Administrative Prevalence of Intellectual Disabilities in Manitoba. Journal on Developmental Disabilities (in Press).

Qiao Y, C Harvard, C Tyson, X Liu, C Fawcett, P Pavlidis, JJA Holden, MES Lewis, E Rajcan-Separovic (2010) Outcome of array CGH analysis for 255 subjects with intellectual disability and search for candidate genes using bioinformatics. Hum Genet 128: 179-184 [Epub May 29 2010] 

Rajcan-Separovic E, Diego-Alvarez D, Robinson WP, Tyson C, Qiao Y, Harvard C, Fawcett C, Kalousek D, Philipp T, Somerville MJ, Stephenson MD.(2010) Identification of copy number variants in miscarriages from couples with idiopathic recurrent pregnancy loss.
Hum Reprod. 2010 Nov;25(11):2913-22. Epub 2010 Sep 16.

Rajcan-Separovic E, Qiao Y, Tyson C, Harvard C, Fawcett C, Kalousek D, Stephenson M, Philipp T. (2010) Genomic changes detected by array CGH in human embryos with developmental defects. Mol Hum Reprod. 2010 Feb;16(2):125-34. Epub 2009 Sep 23.

Regehr K, & Feldman MA (in press). Parent-selected interventions for infants at-risk for autism spectrum disorder and their affected siblings. Behavioral Interventions.

Roy-Wsiaki, G., Marion, C., Martin, G.L., & Yu, C.T. (in press). Teaching a child with autism to request information by asking "what?" Developmental Disabilities Bulletin.

Thomson, K., Walters, K., Martin, G.L., & Yu, C.T. (in press). Treatments for adaptive and social skills. In J.L. Matson & P. Sturmey (Eds.), International Handbook of Autism and Pervasive Developmental Disabilities. New York: Springer Publishing Company.

Ward-King J, Cohen IL, Penning H, Holden JJ. (2010). Brief Report: Telephone Administration of the Autism Diagnostic Interview-Revised: Reliability and Suitability for Use in Research. Journal of Autism and Developmental Disorders. J Autism Dev Disord 40: 1285-1290. [Epub March 23, 2010]

Wegiel J, Kuchna I, Nowicki K, Imaki H, Wegiel J, Marchi E, Ma SY, Chauhan A, Chauhan V, Bobrowicz TW, de Leon M, Louis LA, Cohen IL, London E, Brown WT, & Wisniewski T. (2010). The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes. Acta Neuropathol. 119(6). 755-750.

Zhang H, GN Smith, X Liu, JJA Holden (2010) Association of MAOA, 5HTT and NET promoter polymorphisms, gene expression and protein activity in human placentas. Physiological Genomics 42: 85-92 [Epub March 23, 2010] 



2009

Fazzio, D, Arnal, LYu, CT (2009) Instructing university students to conduct discrete-trials teaching with children with autism. Research in Autism Spectrum Disorders, 3, 57-66.

Hiebert R, Martin GL, Yu CT, Thorsteinsson JR, Martin TL. (2009) Predicting compliance of children with and without developmental delay. Canadian Journal of Behavioural Science/Revue canadienne des sciences du comportement. 41(1), 31-36.

Mazur-Kolecka B, Cohen IL, Jenkins EC, Flory M, Merz G, Brown WT, & Frackowiak J. (2009). Sera from children with Autism alter proliferation of human neuronal progenitor cells exposed to oxidation. Neurotoxicity Research, 16(1). 87-95.

Nguyen DM, CT Yu, TL Martin, P Fregeau, C Pogorzelec & GL Martin (2009). Teaching object-picture matching to improve concordance between objects and pictures preferences for individuals with developmental disabilities: Pilot study. Journal on Developmental Disabilities, 15, 53-64.

Qiao Y, N Riendeau, M Koochek, X Liu, C Harvard, MJ Hildebrand, JJ Holden, ME Lewis, E Rajcan-Separovic (2009) Phenomic determinants of genomic variation in autism spectrum disorders. J Med Genet. 2009 Oct;46(10):680-8. Epub 2009 Jul 21.

Ouellette-Kuntz HM, H Coo, M Lam, CT Yu, MM Breitenbach, PE Hennessey, JJ Holden, HK Brown, AL Noonan, RB Gauthier, LR Crews (2009) Age at Diagnosis of autism spectrum disorders in four regions of Canada. Canadian Journal of Public Health 100: 268-73.

Ouellette-Kuntz HM, Coo H, Lam M, Yu CT, Breitenbach MM, Hennessey PE, Holden JJ, Brown HK, Noonan AL, Gauthier RB, Crews LR. (2009) Age at diagnosis of autism spectrum disorders in four regions of Canada. Can J Public Health. 2009 Jul-Aug;100(4):268-73.

Ouellette-Kuntz, H., Shooshtari, S., Temple, B., Brownell, M., Burchill, C., Yu, C.T., Holden, J.J.A., & Hennen, B. (2009). Estimating administrative prevalence of intellectual disabilities in Manitoba. Journal on Developmental Disabilities, 15(3), 69-80.

Salem, S., Fazzio, D., Arnal, L., Fregeau, P., Thomson, K., Martin, G.L., & Yu, C.T. (2009). A self-instructional package for teaching university students to conduct discrete-trials teaching with children with autism. Journal on Developmental Disabilities, 15, 21-29.

Schwartzman, L. J., Vause, T., Martin, G.L., Yu, C.T., Campbell, L., Danbrook, M., & Feldman, M. (2009). Predicting the learning ability of children with autism: The Assessment of Basic Learning Abilities test versus parents’ predictions. Education and Training on Developmental Disabilities, 44, 271-279.

Thiessen C, Fazzio D, Arnal L, Martin GL, Yu CT, Keilback L. (2009) Evaluation of a self-instructional manual for conducting discrete-trials teaching with children with autism. Behavior Modification. Vol 33(3), May 2009, pp. 360-373

Thomson K, Martin GL, Arnal L, Fazzio D, Yu CT. (2009) Instructing individuals to deliver discrete-trials teaching to children with autism spectrum disorders: A review. Research in Autism Spectrum Disorders. Vol 3(3), Jul-Sep 2009, pp. 590-606

Tyson C, Dawson AJ, Bal S, Tomiuk M, Anderson T, Tucker D, Riordan D, Chudoba I, Morash B, Mhanni A, Chudley AE, McGillivray B, Parslow M, Rappold G, Roeth R, Fawcett C, Qiao Y, Harvard C, Rajcan-Separovic E. (2009) Molecular cytogenetic investigation of two patients with Y chromosome rearrangements and intellectual disability. Am J Med Genet A. 2009 Mar; 149A(3): 490-5

Verbeke, A. K., Martin, G.L., Thorsteinsson, J.R., Murphy, C., & Yu, C.T. (2009). Does mastery of ABLA Level 6 make it easier for individuals with developmental disabilities to learn to name objects? Journal of Behavioral Education, 18, 229-244.


2008

Anisman H, Merali Z, Stead JD. Experiential and genetic contributions to depressive- and anxiety-like disorders: clinical and experimental studies. Neurosci Biobehav Rev. 2008 Aug;32(6):1185-206.

Boycott KM, Parboosingh JS, Chodirker BN, Lowry RB, McLeod DR, Morris J, Greenberg CR, Chudley AE, Bernier FP, Midgley J, Møller LB, Innes AM. Clinical genetics and the Hutterite population: a review of Mendelian disorders. Am J Med Genet A. 2008 Apr 15;146A(8):1088-98. Review.

Chodirker BN, Chudley AE. Routine genetic testing for Asperger syndrome. Genet Med. 2008 Nov;10(11):843-5; author reply 845.

Coo H, Ouellette-Kuntz H, Lloyd JE, Kasmara L, Holden JJ, Lewis ME. Trends in autism prevalence: diagnostic substitution revisited. J Autism Dev Disord. 2008 Jul;38(6):1036-46. (PMID: 17975721)

D'Souza CA, Chopra V, Varhol R, Xie YY, Bohacec S, Zhao Y, Lee LL, Bilenky M, Portales-Casamar E, He A, Wasserman WW, Goldowitz D, Marra MA, Holt RA, Simpson EM, Jones SJ. Identification of a set of genes showing regionally enriched expression in the mouse brain. BMC Neurosci. 2008 Jul 14;9:66.

Gibson WT, Harvard C, Qiao Y, Somerville MJ, Lewis ME, Rajcan-Separovic E. Phenotype-genotype characterization of alpha-thalassemia mental retardation syndrome due to isolated monosomy of 16p13.3. Am J Med Genet A. 2008 Jan 15;146A(2):225-32. Can J Clin Pharmacol. 2008 Summer;15(2):e344-66.

Goh YI, Chudley AE, Clarren SK, Koren G, Orrbine E, Rosales T, Rosenbaum C. Development of Canadian screening tools for fetal alcohol spectrum disorder. Taskforce for Development of FASD Screening Tools. Can J Clin Pharmacol. 2008 Summer;15(2):e344-66.

Hammond P, Forster-Gibson C, Chudley AE, Allanson JE, Hutton TJ, Farrell SA, McKenzie J, Holden JJ, Lewis ME. Face-brain asymmetry in autism spectrum disorders. Mol Psychiatry. 2008 Jun;13(6):614-23. (PMID: 18317467)

Hettinger JA, Liu X, Schwartz CE, Michaelis RC, Holden JJ. A DRD1 haplotype is associated with risk for autism spectrum disorders in male-only affected sib-pair families. Am J Med Genet B Neuropsychiatr Genet. 2008 Jul 5;147B(5):628-36. (PMID: 18205172)

Hettinger JA, Liu X, Holden JJ.The G22A polymorphism of the ADA gene and susceptibility to autism spectrum disorders. J Autism Dev Disord. 2008 Jan;38(1):14-9. (PMID: 17340203)

Lee, M.S.H., Nguyen, D., Yu, C.T., Thorsteinsson, J.R., Martin, T.L., & Martin, G.L. (2008). Discrimination skills predict effective preference assessment methods. Education and Training in Developmental Disabilities, 43, 388-396.

Liu X, Novosedlik N, Wang A, Hudson ML, Cohen IL, Chudley AE, Forster-Gibson CJ, Lewis SM, Holden JJ. The DLX1and DLX2 genes and susceptibility to autism spectrum disorders. Eur J Hum Genet. 2008 Aug 27. (PMID: 18728693)

Martin GL, Thorsteinsson JR, Yu CT, Martin TL, Vause T. The assessment of basic learning abilities test for predicting learning of persons with intellectual disabilities: a review. Behav Modif. 2008 Mar;32(2):228-47. Review.

Merali Z, Anisman H, James JS, Kent P, Schulkin J. Effects of corticosterone on corticotrophin-releasing hormone and gastrin-releasing peptide release in response to an aversive stimulus in two regions of the forebrain (central nucleus of the amygdala and prefrontal cortex). Eur J Neurosci. 2008 Jul;28(1):165-72.

Merali Z, Cayer C, Kent P, Anisman H. Nesfatin-1 increases anxiety- and fear-related behaviors in the rat. Psychopharmacology (Berl). 2008 Nov;201(1):115-23.

Mistry M, Pavlidis P. Gene Ontology term overlap as a measure of gene functional similarity. BMC Bioinformatics. 2008 Aug 4;9:327.

Mittleman G, Goldowitz D, Heck DH, Blaha CD. Cerebellar modulation of frontal cortex dopamine efflux in mice: relevance to autism and schizophrenia. Synapse. 2008 Jul;62(7):544-50.

Murphy, C., Figueroa, M., Martin, G.L., Yu, C.T., & Figueroa, J. (2008). The use of computer-generated fading materials to teach visual-visual non-identity matching tasks. Developmental Disabilities Bulletin, 36, 49-66.

Qiao Y, Liu X, Harvard C, Hildebrand MJ, Rajcan-Separovic E, Holden JJ, Lewis ME. Autism-associated familial microdeletion of Xp11.22. Clin Genet. 2008 Aug;74(2):134-44. (PMID: 18498374)

Rusnak AJ, Hadfield MI, Chudley AE, Marles SL, Reid GJ, Chodirker BN. Increased Nuchal Translucency Thickness: A Potential Indicator for Ritscher-Schinzel Syndrome. Fetal Diagn Ther. 2008 Oct 28;24(4):395-399.

Spevack, S., Wright, L., Yu, C.T., Walters, K., & Holborn, S. (2008). Passive and active approach responses in preference assessment for children with profound multiple disabilities and minimal movement. Journal on Developmental Disabilities, 14, 61-68.

Stark KL, Xu B, Bagchi A, Lai WS, Liu H, Hsu R, Wan X, Pavlidis P, Mills AA, Karayiorgou M, Gogos JA. Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet. 2008 Jun;40(6):751-60.

Tyson C, Qiao Y, Harvard C, Liu X, Bernier FP, McGillivray B, Farrell SA, Arbour L, Chudley AE, Clarke L, Gibson W, Dyack S, McLeod R, Costa T, Vanallen MI, Yong SL, Graham GE, Macleod P, Patel MS, Hurlburt J, Holden JJ, Lewis SM, Rajcan-Separovic E. Submicroscopic deletions of 11q24-25 in individuals without Jacobsen syndrome: re-examination of the critical region by high-resolution array-CGH. Mol Cytogenet. 2008 Nov 11;1(1):23. (PMID: 19000322)

 


2007


Arnal, L., Fazzio, D., Martin, G., Yu, C.T., Keilback, L., & Starke, M. (2007). Instructing university students to conduct discrete-trials teaching with confederates simulating children with autism. Developmental Disabilities Bulletin, 35, 131-147.

Bao L, Peirce JL, Zhou M, Li H, Goldowitz D, Williams RW, Lu L, Cui Y. An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypes. Hum Mol Genet. 2007 Jun 1;16(11):1381-90.

Doan, L.A., Martin, T.L., Yu, C.T., & Martin, G.L. (2007). Do ABLA test results predict performance on three-choice discriminations for persons with developmental disabilities? Journal on Developmental Disabilities, 13, 1-11.

Feldman M, McDonald L, Serbin L, Stack D, Secco ML, Yu CT. Predictors of depressive symptoms in primary caregivers of young children with or at risk for developmental delay. J Intellect Disabil Res. 2007 Aug;51(Pt 8):606-19.

Fisch GS, Carpenter N, Howard-Peebles PN, Holden JJ, Tarleton J, Simensen R, Nance W. Studies of age-correlated features of cognitive-behavioral development in children and adolescents with genetic disorders. Am J Med Genet A. 2007 Oct 15;143A(20):2478-89. (PMID: 17853466)

Ouellette-Kuntz H, Coo H, Lloyd JE, Kasmara L, Holden JJ, Lewis ME. Trends in special education code assignment for autism: implications for prevalence estimates. J Autism Dev Disord. 2007 Nov;37(10):1941-8. (PMID: 17216561)

Thomson, KM, Czarnecki, D., Martin, T.L., Yu, C.T., & Martin, G.L. (2007). Predicting optimal preference assessment methods for individuals with developmental disabilities. Education and Training in Developmental Disabilities, 42(1), 107-114.

Thorsteinsson, J.R., Martin, G.L., Yu, C.T., Spevack, S.M., Martin, T.L., & Lee, M.S. (2007). Predicting the learning ability of people with intellectual disabilities: The Assessment of Basic Learning Abilities test versus caregivers. American Journal on Mental Retardation, 112, 130-139.
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